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Product Name Anti-BIN1 antibody (monoclonal)
Description Mouse IgG monoclonal antibody for BIN1, bridging integrator 1
(BIN1) detection. Tested with WB, IHC-F, ICC in Human; mouse
rat. No cross reactivity with other proteins.
Host Mouse
Target Species Human, Mouse, Rat
Application WB,HC-P, IHC-F, ICC,
Recommended Detection Systems
We recommends Enhanced Chemiluminescent Kit with anti-Mouse IgG (EK1001) for Western blot, and HRP Conjugated anti-Mouse IgG Super Vision Assay Kit (SV0001-1) for IHC(P), IHC(F) and ICC.
*Blocking peptide can be purchased. Contact us for more information
Immunogen: Recombinant polypeptide containing amino acids 189-398 of  human Bin1.
Specificity No cross reactivity with other proteins
Pack Size 100?g/vial
Catalog Number Ab1005

Background:
BIN1(AMPH2) is a novel human gene product with features of a tumor suppressor
protein. BIN1 gene to chromosome 2q14. Loss of BIN1 expression appears to be a
frequent aberration in human hepatocellular carcinomas . mutations in BIN1 cause
centronuclear myopathy by interfering with remodeling of T tubules and/or endocytic
membranes, and that the functional interaction between BIN1 and DNM2 is necessary
for normal muscle function and positioning of nuclei.
Product Properties:
Clonality Monoclonal
Clone Number 99D
Form Lyophilized
Contents Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
*carrier free antibody available upon request.
Reconstitution Add 1ml of 1XPBS buffer (catalog # 1XPBS-001) will yield a concentration of 100ug/ml.
Storage At -20?C for one year. After reconstitution, at 4?C for one month. It can also be aliquoted and stored frozen at -20?C for a longer time. Avoid repeated freezing and thawing.
Purification Ascites