Human Recombinant Collagen alpha-1(VIII) chain (from Cells)
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$1,216.71
Product Name : Human Recombinant Collagen alpha-1(VIII) chain (from Cells)
Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endothelium. COL8A1 forms homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 contains one C1q domain and is primarily expressed in the subendothelium of large blood vessels. The expression level can be up-regulated during vascular injury, in atherosclerosis and in diabetes. COL8A1 may have a role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.
- Fusion-Tag: C-6 His tag
| Protein/peptide name | Collagen alpha-1(VIII) chain |
| Protein synonyms | Endothelial Collagen,Collagen Alpha-1(VIII) Chain,C3orf7,COL8A1,Vastatin |
| Protein/peptide type | Recombinant |
| Species | Human |
| Source | Cells |
| Sequence | Gly28-Met744 |
| Endotoxin content | <0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
| Purity | > 95% as determined by reducing SDS-PAGE |
| Formulation | Lyophilized from a 0.2 um filtered solution of 20mM Tris,150mM NaCl,pH8.0. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Molecular weight | 71.6 kD |
| Storage conditions | Lyophilized protein should be stored at ?20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at ?20 °C for 3 months. |
| Tag sequence | C-6 His tag |
| Tested applications | Bioassay |
| Molecular weight | 71.6 kD |
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