Human Recombinant Anthrax Toxin Receptor 1
Price:
$996.93
Product Name : Human Recombinant Anthrax Toxin Receptor 1
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It is also involved in the angiogenic response of cultured umbilical vein endothelial cells, up-regulated in cultured angiogenic umbilical vein endothelial cells. Defects in ANTXR1 are associated with susceptibility to hemangioma capillary infantile (HCI).
- Fusion-Tag: C-6 His tag
This recombinant protein can be used for biological assays. For research use only.
| Protein/peptide name | Anthrax Toxin Receptor 1 |
| Protein synonyms | Anthrax Toxin Receptor 1,TEM8,Tumor Endothelial Marker 8,ANTXR1,ATR |
| Protein/peptide type | Recombinant |
| Species | Human |
| Source | Cells |
| Sequence | Glu33-Lys321 |
| Endotoxin content | <0.1 ng/ug (1 IEU/ug) as determined by LAL test. |
| Purity | > 95% as determined by reducing SDS-PAGE |
| Formulation | Lyophilized from a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the Lyophilized protein in ddH2O. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
| Molecular weight | 33.56 kD |
| Storage conditions | Lyophilized protein should be stored at ?20 °C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 4-7 °C for 2-7 days. Aliquots of reconstituted samples are stable at ?20 °C for 3 months. |
| Tag sequence | C-6 His tag |
| Tested applications | Bioassay |
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