Human Recombinant PECAM-1
Price:
$602.43
Product Name : Human Recombinant PECAM-1
PECAM is transmembrane glycoprotein that belongs to the Ig-related superfamily of adhesion molecules. It is highly expressed at endothelial cell junctions, and is also expressed in platelets and most leukocyte sub-types. The primary function of PECAM-1 is the mediation of leukocyte-endothelial cell adhesion and signal transduction. PECAM-1 has been implicated in the pathogenesis of various inflammation-related disorders, including thrombosis, multiple sclerosis (MS), and rheumatoid arthritis. The human PECAM-1 gene codes for a 738 amino acid transmembrane glycoprotein that contains a 118 amino acid cytoplasmic domain, a 19 amino acid transmembrane domain, and a 574 amino acid extracellular domain. Recombinant Human PECAM-1 is a 572 amino acid glycoprotein comprising the extracellular domain of PECAM-1. Monomeric glycosylated PECAM-1 migrates at an apparent molecular weight of approximately 80.0-95.0 kDa by SDS-PAGE analysis under reducing conditions. The calculated molecular weight of Recombinan Human PECAM-1 is 64.3 kDa.
Ordering information: For research use only. Not for use in diagnostic or therapeutic procedures.
| Protein/peptide name | PECAM-1 |
| Protein synonyms | Platelet Endothelial Cell Adhesion Molecule,PECAM1,EndoCAM,CD31 antigen |
| Protein/peptide type | Recombinant |
| Protein Function | Cytokines and Growth Factors |
| Species | Human |
| Source | HEK293 cells |
| Conjugation | Unconjugated |
| Gene ID | 5175 P16284 |
| Sequence | ENSFTINSVD MKSLPDWTVQ NGKNLTLQCF ADVSTTSHVK PQHQMLFYKD DVLFYNISSM KSTESYFIPE VRIYDSGTYK CTVIVNNKEK TTAEYQLLVE GVPSPRVTLD KKEAIQGGIV RVNCSVPEEK APIHFTIEKL ELNEKMVKLK REKNSRDQNF VILEFPVEEQ DRVLSFRCQA RIISGIHMQT SESTKSELVT VTESFSTPKF HISPTGMIME GAQLHIKCTI QVTHLAQEFP EIIIQKDKAI VAHNRHGNKA VYSVMAMVEH SGNYTCKVES SRISKVSSIV VNITELFSKP ELESSFTHLD QGERLNLSCS IPGAPPANFT IQKEDTIVSQ TQDFTKIASK SDSGTYICTA GIDKVVKKSN TVQIVVCEML SQPRISYDAQ FEVIKGQTIE VRCESISGTL PISYQLLKTS KVLENSTKNS NDPAVFKDNP TEDVEYQCVA DNCHSHAKML SEVLRVKVIA PVDEVQISIL SSKVVESGED IVLQCAVNEG SGPITYKFYR EKEGKPFYQM TSNATQAFWT KQKASKEQEG EYYCTAFNRA NHASSVPRSK ILTVRVILAP WK |
| Protease-free | Y |
| Endotoxin level | Low |
| Endotoxin content | >0.1 ng/?g |
| Biological activity | Biological Activity tests can vary. Please refer to the Product CoA for information. |
| Purity | 0.97 |
| Form | Lyophilized |
| Formulation | Formulation can vary. Please refer to product CoA for information. |
| Molecular weight | 64.3 kDa |
| Reconstitution instructions | Reconstitution instructions can vary. Please refer to the product CoA for info. |
| Storage conditions | Store at –20 °C prior to reconstitution. |
| Shipping temperature | Ambient |
| Molecular weight | 64.3 kDa |
There have been no reviews for this product yet.
